PQQ

Pyrroloquinoline quinone, stimulus for new mitochondria.

PQQ – Pyrroloquinoline quinone
Introduction

The molecule of mitochondrial biogenesis

PQQ is a natural molecule with a dual action that is precious for cellular longevity: on one side it is a potent and particularly stable antioxidant, on the other it stimulates the natural formation of new mitochondria, the energy centres of our cells.

This double mechanism makes it a much appreciated ingredient for the support of energy and of physical and mental vitality, and it is frequently paired with other mitochondrial actives such as CoQ10 in the most advanced formulations.

What is PQQ

Pyrroloquinoline quinone is present in foods such as kiwi, green peppers, natto, parsley and green tea, although in quantities far below those used in supplementation.

Its chemical structure makes it exceptionally stable in redox reactions, a property that distinguishes it from most dietary antioxidants.

Role in Longevity and Healthy Aging

PQQ activates mitochondrial biogenesis through PGC-1α and exerts a very stable antioxidant action.

Acting on the creation of new mitochondria means intervening on the quantity of the cellular energy machinery, a complementary approach to those ingredients that support the function or the turnover of existing mitochondria.

Nutraceutical Applications

PQQ is formulated in capsules, frequently in blends with CoQ10 for energy and mitochondrial vitality formulations.

The pairing with CoQ10 follows a precise logic: PQQ stimulates the creation of new mitochondria, CoQ10 supports their function.

Naturally Found In

  • Kiwi
  • Green peppers
  • Natto
  • Parsley and green tea

Synergies

  • Coenzyme Q10 – PQQ creates new mitochondria, CoQ10 supports their function
  • Urolithin A – Mitochondrial biogenesis combined with mitophagy
  • NAD+ precursors (NR, NMN) – Overall support to cellular energy metabolism
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